牙周疾病无小事,妊娠期女性需注意(综述)
创作:Epi汪 审核:Epi汪 2021年10月15日
  • 尽管机制尚不完全清楚,但已经发现,怀孕期间激素变化会导致牙龈炎症增加;
  • 同样,一些观察性研究证据表明,孕期牙周病与不良妊娠结局风险增高有关,包括早产、低出生体重等,但其中的因果关系不明;
  • 不同研究的异质性可能来源于牙周炎诊断标准差异、治疗方案差异以及诸多混杂因素的影响;
  • 有研究发现,非酒精类抗菌漱口水,可以降低早产风险;
  • 未来的研究应致力于开展高质量的随机对照试验,证明怀孕与牙周病之间的因果关联。
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Epi汪
大量的研究发现,妊娠期牙周病发生呈现一定特点,同时妊娠期牙周病可能与不良妊娠结局之间也存在关联。但是这二者之间是否存在因果关联,以及因果关联的方向并不确定。本综述基于目前的研究证据进行了综述总结,为进一步开展相关研究提供了理论依据。
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Periodontology 2000 [IF:12.239]

Periodontology and pregnancy: An overview of biomedical and epidemiological evidence

牙周病学与妊娠:生物医学和流行病学证据综述

10.1111/prd.12394

2021-08-31, Review

Abstract & Authors:展开

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Women are particularly susceptible to developing gingival problems during pregnancy. In addition, periodontal disease in pregnant women may lead to adverse outcomes for both mother and infant, which have serious clinical and public health implications. Both scenarios have been extensively researched, helping to bring attention to pregnant women as an important and vulnerable population as it concerns periodontal health. The increase in gingival inflammation caused by hormonal changes in pregnant women is undisputed and has been studied and documented since the 1960s, although the exact etiology is not fully understood. The relationship between periodontal disease during pregnancy and adverse pregnancy outcomes is less substantiated, because of conflicting evidence. This review of the biomedical and epidemiologic literature provides an overview of both sides of this relationship and examines the potential mechanisms for developing periodontal disease during pregnancy and the proposed mechanisms by which periodontal disease leads to adverse pregnancy outcomes.

First Authors:
Karen Raju

Correspondence Authors:
Lisa Berens

All Authors:
Karen Raju,Lisa Berens

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