不健康饮食或增加哮喘风险
创作:白蓝木 审核:aluba 03月09日
  • 纳入406名6-14岁的波多黎各青少年,在9-20岁时进行再次随访;
  • 基于饮食评分评估饮食状况,不健康饮食表现为蔬菜及谷物摄入减少、乳制品及甜食摄入增加;
  • 171名受试者在2次随访中均被评估为健康饮食,72名受试者在2次随访中均被评估为不健康饮食,86名受试者及77名受试者分别在第一次及第二次随访中被评估为不健康饮食;
  • 多变量分析结果显示,在2次随访中均为不健康饮食与哮喘及严重哮喘恶化的风险增加相关,但与肺功能的变化无关。
主编推荐语
aluba
波多黎各青年的哮喘比例偏高,较差的饮食质量可能是原因之一。The journal of allergy and clinical immunology: In practice上发表的一项前瞻性队列研究结果,对406名波多黎各青少年进行约5年的随访后发现,不健康饮食与哮喘及严重哮喘恶化风险增加相关。
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Diet, asthma, and severe asthma exacerbations in a prospective study of Puerto Rican youth

一项针对波多黎各青年的前瞻性研究中的饮食、哮喘和严重哮喘发作

10.1016/j.jaip.2022.01.029

02-01, Article

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BACKGROUND: Poor diet quality may contribute to the disproportionate asthma burden in Puerto Rican youth.
OBJECTIVE: To examine whether an unhealthy diet at one or two study visits conducted over ∼5 years is associated with asthma, severe asthma exacerbations, and worse lung function in Puerto Rican youth.
METHODS: Prospective study of 406 Puerto Rican youth aged 6-14 years at a baseline visit and 9-20 years at a follow-up visit. As in prior work, diet was assessed using a dietary score ranging from -2 to +2. Our exposure of interest was an unhealthy diet, defined as a non-positive dietary score (0 to -2) at one or both visits. Our outcomes of interest were asthma (defined as physician-diagnosed asthma and ≥1 episode of wheeze in the year prior to the second visit), ≥1 severe asthma exacerbation in the year prior to the second visit, and change in percent predicted lung function measures (FEV, FVC, and FEV/FVC) between the first and second visits.
RESULTS: In a multivariable analysis, an unhealthy diet at both visits was associated with increased odds of asthma (adjusted odds ratio [aOR]=3.38, 95% confidence interval [CI]=1.74 to 6.57) and severe asthma exacerbations (aOR=2.65, 95% CI=1.16 to 6.03), but not with change in lung function.
CONCLUSIONS: An unhealthy diet at both visits was associated with increased odds of asthma and severe asthma exacerbations compared with a healthy diet at both visits. Our findings support health policies promoting a healthy diet in Puerto Rican youth, a population at high risk for asthma.

First Authors:
Jessica Reyes-Angel

Correspondence Authors:
Juan C Celedón

All Authors:
Jessica Reyes-Angel,Yueh-Ying Han,Franziska Rosser,Erick Forno,Edna Acosta-Pérez,Glorisa Canino,Juan C Celedón

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