国内团队:孕前吃的好,母婴更健康
创作:Epi汪 审核:Epi汪 2021年12月03日
  • 检索并筛查相关文献,最终纳入65篇前瞻性研究共计83万余名研究对象的数据;
  • 总体结果表明,孕前摄入油炸食品、快餐、红肉和加工肉,或者血红素铁和低碳水化合物饮食模式与妊娠期糖尿病(GDM)呈正相关;
  • 而孕前高膳食纤维和叶酸补充与GDM风险呈负相关;
  • 孕前母亲咖啡因摄入增加自然流产的风险,而叶酸补充对总不良新生儿结局、早产和小于胎龄儿具有保护作用;
  • 未发现孕前含糖饮料、马铃薯等摄入量与妊娠结局的关联。
主编推荐语
Epi汪
怀孕前保持健康饮食,摄入富含促进健康的营养素,如膳食纤维、叶酸和一些抗氧化剂和维生素,可能在预防不良孕产妇和新生儿结局方面发挥有益作用。此外,减少不健康地食用油炸食品、快餐、红肉和加工肉,以及富含血红素铁或咖啡因的食品,可能有助于预防不良的孕产妇和新生儿结局。本研究为指导备孕期饮食提供了科学依据。
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Association of maternal pre-pregnancy dietary intake with adverse maternal and neonatal outcomes: A systematic review and meta-analysis of prospective studies

孕妇孕前饮食摄入与不良孕产妇和新生儿结局的关联:前瞻性研究的系统评价和荟萃分析

10.1080/10408398.2021.1989658

2021-10-20, Article

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This study aimed to summarize the evidence regarding the effects of dietary intake before conception on pregnancy outcomes by performing a systematic review and meta-analysis of prospective studies. Electronic databases were searched from inception up to August 2021. Overall, 65 studies involving 831 798 participants were included and 38 studies were quantitatively pooled. With regard to maternal outcomes, pre-pregnancy intake of fried food, fast food, red and processed meat, heme iron and a low-carbohydrate dietary pattern was positively associated with the risk of gestational diabetes mellitus (GDM) (all P < 0.05). However, a high dietary fiber intake and folic acid supplementation were negatively associated with GDM risk (both P < 0.05). With regard to neonatal outcomes, maternal caffeine intake before pregnancy significantly increased the risk of spontaneous abortion, while folic acid supplementation had protective effects on total adverse neonatal outcomes, preterm birth, and small-for-gestational age (SGA, all P < 0.05). However, no significant associations were found between adverse pregnancy outcomes (i.e., GDM and SGA) and the pre-pregnancy dietary intake of sugar-sweetened beverages, potato, fish, and carbohydrates and the Healthy Eating Index. Our study suggests that maintaining a healthy diet before conception has significant beneficial effects on pregnancy outcomes.

First Authors:
Yunfeng Cui,Minqi Liao,Aihua Xu

Correspondence Authors:
Donghong Wang,Fangfang Zeng

All Authors:
Yunfeng Cui,Minqi Liao,Aihua Xu,Gengdong Chen,Jun Liu,Xiaoxuan Yu,Shuna Li,Xingyao Ke,Sixian Tan,Zeyan Luo,Qian Wang,Yanhua Liu,Donghong Wang,Fangfang Zeng

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