肠道菌群与肥胖及其他相关代谢紊乱之间的联系
  • 越来越多的证据表明肠道菌群与遗传易感性或饮食改变之间的互作,可能是肥胖及其他代谢疾病的关键影响因素;
  • 弄清肠道菌群影响肥胖及其他相关的慢性代谢疾病背后的机制十分重要;
  • 对以肠道菌群为靶点来预防及控制代谢疾病有很大帮助。
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The crosstalk between gut microbiota and obesity and related metabolic disorders

10.2217/fmb-2015-0024

2016-05-18, Review

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Obesity and related metabolic diseases are currently a threat to global public health. The occurrence and development of these conditions result from the combined effects of multiple factors. The human gut is a diverse and vibrant microecosystem, and its composition and function are a focus of research in the fields of life science and medicine. An increasing amount of evidence indicates that interactions between the gut microbiota and their genetic predispositions or dietary changes may be key factors that contribute to obesity and other metabolic diseases. Defining the mechanisms by which the gut microbiota influence obesity and related chronic metabolic diseases will bring about revolutionary changes that will enable practitioners to prevent and control metabolic diseases by targeting the gut microbiota.

First Authors:
Wen-Ting Xu

Correspondence Authors:
Zhen Yang,Nonghua Lu

All Authors:
Wen-Ting Xu,Yongzhan Nie,Zhen Yang,Nonghua Lu

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