Abstract & Authors:展开
Interaction between humans and the gut microbiota is important for human physiology. Here, the gut microbiota was analyzed via metagenomic sequencing, and the fluctuations in the gut microbiota under the conditions of spaceflight were characterized. The composition and function of the gut microbiota were substantially affected by spaceflight; however, individual specificity was uncompromised. We further confirmed the species fluctuations and functional genes from both missions. Resistance and virulence genes in the gut microbiota were affected by spaceflight, but the species attributions remained stable. Spaceflight markedly affected the composition and function of the human gut microbiota, implying that the human gut microbiota is sensitive to spaceflight.
Shukuan Ling,Yingxian Li
Zizhong Liu,Gui Luo,Ruikai Du,Weijia Sun,Jianwei Li,Haiyun Lan,Pu Chen,Xinxin Yuan,Dengchao Cao,Yuheng Li,Caizhi Liu,Shuai Liang,Xiaoyan Jin,Ruifu Yang,Yujing Bi,Yanping Han,Ping Cao,Wei Zhao,Shukuan Ling,Yingxian Li