高脂低碳水+植物性蛋白饮食有益于牙周健康
创作:aluba 审核:aluba 01月02日
  • 67名中老年受试者(65-75岁)随机分为4组,分别摄入高脂低碳水+杂食性蛋白来源、低脂高碳水+杂食性蛋白来源、高脂低碳水+半素食性蛋白来源、低脂高碳水+半素食性蛋白来源;
  • 杂食性蛋白来源为50%动物蛋白+50%植物蛋白,半素食性蛋白来源为30%动物蛋白+70%植物蛋白,干预持续4周;
  • 在高脂低碳水+半素食性蛋白来源组的受试者中,临床附着水平<5mm的数量显著增加,龈沟液显著减少;
  • 临床指标与受试者的口腔菌群的变化无关。
主编推荐语
aluba
Journal of Clinical Periodontology上发表的一项随机临床试验结果,对67名中老年受试者进行4周干预,发现高脂低碳水+半素食性蛋白来源饮食(41%脂肪、41%碳水化合物、14%蛋白,蛋白来源为70%植物性蛋白+30%动物性蛋白)对多种牙周健康指标有改善作用。
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A randomised clinical trial to investigate the effect of dietary protein sources on periodontal health

一项随机对照试验用于研究膳食蛋白来源对牙周健康的影响

10.1111/jcpe.13587

2021-12-21, Article

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AIM: The aim was to assess two macronutrient interventions in a 2x2 factorial dietary design to determine their effects on oral health.
MATERIALS AND METHODS: Participants (65-75 years old) with a BMI between 20-35 kg/m of a larger RCT who consented to an oral health assessment were recruited. They had ad libitum access to one of four experimental diets (omnivorous higher fat or higher carbohydrate, semi-vegetarian higher fat or higher carbohydrate) for 4 weeks. Periodontal examination included periodontal probing depth (PPD), clinical attachment level (CAL) and bleeding on probing. Oral plaque and gingival crevicular fluid (GCF) were collected before and after the intervention.
RESULTS: Between baseline and follow up the number of sites with a CAL <5 mm (mean difference (MD) -5.11±9.68, P=0.039) increased and the GCF amount (MD -23.42±39.42 Periotron Units (PU), P=0.050) decreased for the semi-vegetarian high fat diet. For the mean proportion of sites with PPD reduction >1 mm and CAL gain >1 mm significant differences were calculated between the diets investigated. The clinical parameters were not associated with changes of the oral microbiota.
CONCLUSION: The results of this study provided evidence that a semi-vegetarian higher fat diet provides benefits to clinical parameters of periodontal health. ACTRN12616001606471. This article is protected by copyright. All rights reserved.

First Authors:
Joerg Eberhard

Correspondence Authors:
Joerg Eberhard

All Authors:
Joerg Eberhard,Kate Ruiz,Jian Tan,Thilini N Jayasinghe,Shahrukh Khan,Elif Eroglu,Christina Adler,Stephen J Simpson,David G Le Couteur,David Raubenheimer,Laurence Macia,Alison K Gosby,Rosilene V Ribeiro

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