吴浩

瑞典哥德堡大学博士后

教育经历

  • 2002-2006,本科,山东理工大学生命科学院;生物工程专业;导师:张红雨教授
  • 2007-2012,博士,浙江大学沃森基因研究院;生物信息学专业;导师:于军教授

工作经历

  • 2012-2015,助研,中国科学院北京基因组研究所;细菌基因组进化
  • 2015-至今,博后,瑞典哥德堡大学Sahlgrenska医院;肠道菌与健康;导师:Fredrik Backhed

主要研究领域与方向

  • 肠道菌与各类心血管及代谢类疾病的相互作用;多组学数据整合;细菌基因组进化

著作

  • Ara Koh, Antonio Molinaro, Marcus Ståhlman, Muhammad-Tanweer Khan, Caroline Schmidt, Hao Wu, Alba Carreras, Louise Olofsson, Louise Mannerås-Holm, Victor Gerdes, Annick Hartstra, Maurits de Brauw, Rosie Perkins, Max Nieuwdorp, Göran Bergström, Fredrik Bäckhed. Microbially produced imidazole propionate impairs insulin signaling through mTORC1. Cell. 2018. P947-961.E17 [Highlighted in Nature Reviews Endocrinology]
  • Adil Mardinoglu*, Hao Wu*, Elias Bjornson, Cheng Zhang, Antti Hakkarainen, Sari M. Räsänen, Sunjae Lee, Rosellina M. Mancina, Mattias Bergentall, Leonie Bogl, Kirsi H. Pietiläinen, Sanni Söderlund, Niina Matikainen, Marcus Ståhlman, Per-Olof Bergh, Martin Adiels, Brian D. Piening, Marit Granér, Nina Lundbom4, Kevin J. Williams, Stefano Romeo, Jens Nielsen, Michael Snyder, Mathias Uhlén, Göran Bergström, Rosie Perkins, Hanns-Ulrich Marschall, Fredrik Bäckhed, Marja-Riitta Taskinen and Jan Borén. An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans. Cell Metabolism. 2018: 559-571 [Highlighted in GUT, and Science Translational Medicine]
  • Hao Wu*, Eduardo Esteve*, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås-Holm, Marcus Ståhlman, Lisa M Olsson, Matteo Serino, Mercè Planas-Fèlix, Gemma Xifra, Josep M Mercader, David Torrents, Rémy Burcelin, Wifredo Ricart, Rosie Perkins, José Manuel Fernàndez-Real & Fredrik Bäckhed. Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. 2017. Nature Medicine 23, 850–858 doi:10.1038/nm.4345 [Highlighted in Nature Reviews Gastroenterology & Hepatology, Nature Reviews Endocrinology, and Cell Metabolism] [Recommended by F1000]
  • Hao Wu*, Valentina Tremaroli*, Fredrik Bäckhed. Linking Microbiota to Human Diseases: A Systems Biology Perspective. Trends in Endocrinology & Metabolism. 2015, DOI: j.tem.2015.09.011.
  • Hao Wu, Yongjun Fang, Jun Yu, Zhang Zhang. The quest for a unified view of bacterial land colonization. ISME J, 2014, doi: 10.1038/ismej.2013.247. [Recommended by F1000]