饮食的升糖指数或与疾病风险无关

纳入73项随机对照试验或观察性研究进行荟萃分析;
饮食的升糖指数(GI)或升糖反应(GR)与疾病结果(心血管疾病、糖尿病和肥胖)的关系不明确;
最有力的干预研究显示GI/GR与疾病风险的生理指标之间几乎无关;
观察性研究对GI/GR与疾病结果的关系证据有限;
食物或膳食的GI不太可能与疾病风险或健康结果有关,膳食纤维或全谷物或许能更好的预测健康结果;
注重整体饮食质量,增加膳食纤维、水果和蔬菜的摄入或有助于降低慢性病风险。
延伸阅读
Nutrients [IF:4.196]

Relevance of the Glycemic Index and Glycemic Load for Body Weight, Diabetes, and Cardiovascular Disease

升糖数和糖负荷与体重、糖尿病和心血管疾病的相关性

09-22, Review, 10.3390/nu10101361more

Abstract:
Despite initial enthusiasm, the relationship between glycemic index (GI) and glycemic response (GR) and disease prevention remains unclear. This review examines evidence from randomized, controlled trials and observational studies in humans for short-term (e.g., satiety) and long-term (e.g., weight, cardiovascular disease, and type 2 diabetes) health effects associated with different types of GI diets. A systematic PubMed search was conducted of studies published between 2006 and 2018 with key words glycemic index, glycemic load, diabetes, cardiovascular disease, body weight, satiety, and obesity. Criteria for inclusion for observational studies and randomized intervention studies were set. The search yielded 445 articles, of which 73 met inclusion criteria. Results suggest an equivocal relationship between GI/GR and disease outcome. The strongest intervention studies typically find little relationship among GI/GR and physiological measures of disease risk. Even for observational studies, the relationship between GI/GR and disease outcomes is limited. Thus, it is unlikely that the GI of a food or diet is linked to disease risk or health outcomes. Other measures of dietary quality, such as fiber or whole grains may be more likely to predict health outcomes. Interest in food patterns as predictors of health benefits may be more fruitful for research to inform dietary guidance.

First Authors:
Sonia Vega-López

Correspondence Authors:
Sonia Vega-López

All Authors:
Sonia Vega-López,Bernard J Venn,Joanne L Slavin