【食品营养】体外消化研究巴西莓多酚对肠道健康的益处
  • 本文在体外模拟消化巴西莓,随后经模拟人大肠末端的厌氧分批培养发酵模型发酵,探讨其益生功能和对结肠的抗遗传毒性作用。
  • 体外消化后,49.8%的总多酚可被利用。
  • 与阴性对照相比,粪便接种混合培养发酵后,拟杆菌属普氏菌spp.和溶组织梭菌群数量下降,总短链脂肪酸含量增加。
  • 经体外消化和发酵,样品仍保持着显著的抗氧化和抗遗传毒性作用。
  • 本研究为体外结果,需要进行饮食干预研究,以证明食用巴西莓对肠道健康有益。
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Food Chemistry [IF:5.399]

In vitro approaches to assess the effects of açai (Euterpe oleracea) digestion on polyphenol availability and the subsequent impact on the faecal microbiota

体外方法评估巴西莓消化作用对多酚的可用性和随后对粪便菌群的影响

10.1016/j.foodchem.2017.04.164

2017-11-01, Article

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A considerable proportion of dietary plant-polyphenols reach the colon intact; determining the effects of these compounds on colon-health is of interest. We hypothesise that both fibre and plant polyphenols present in açai (Euterpe oleracea) provide prebiotic and anti-genotoxic benefits in the colon. We investigated this hypothesis using a simulated in vitro gastrointestinal digestion of açai pulp, and a subsequent pH-controlled, anaerobic, batch-culture fermentation model reflective of the distal region of the human large intestine. Following in vitro digestion, 49.8% of the total initial polyphenols were available. In mixed-culture fermentations with faecal inoculate, the digested açai pulp precipitated reductions in the numbers of both the Bacteroides-Prevotella spp. and the Clostridium-histolyticum groups, and increased the short-chain fatty acids produced compared to the negative control. The samples retained significant anti-oxidant and anti-genotoxic potential through digestion and fermentation. Dietary intervention studies are needed to prove that consuming açai is beneficial to gut health.

First Authors:
Randah M Alqurashi

Correspondence Authors:
Randah M Alqurashi

All Authors:
Randah M Alqurashi,Sehad N Alarifi,Gemma E Walton,Adele F Costabile,Ian R Rowland,Daniel M Commane

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