绿茶改善非酒精性脂肪肝

铁螯合剂抗氧化疗法是治疗脂肪肝的一种方式,本文评估绿茶的抗氧化性、铁螯合能力,以及对糖脂代谢的影响。
非酒精性脂肪肝患者随机分为两组进行双盲试验,周期三个月;干预组(21人)每天给予550 mg的绿茶片剂和营养教育,对照组(24人)采用安慰剂替代疗法。
结果显示,相对于对照组,干预组的BMI、天冬氨酸转氨酶(AST)、空腹血糖(FBS)显著改善。
铁结合力(TIBC)、铁蛋白、丙氨酸转氨酶(ALT)、稳态和体重没有显著性差异。
延伸阅读

Hepatitis Monthly [IF:1.578]

Green Tea in Non-Alcoholic Fatty Liver Disease; A Double Blind Randomized Clinical Trial

绿茶对非酒精性脂肪肝病的影响:一组双盲随机临床试验

10.5812/hepatmon.14993

2017-09-10, Article

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Objectives: Antioxidant treatment with Iron chelating agents is one of the suggested treatments for fatty liver disease, which has become an important health problem in the recent decades. In this study the authors evaluated the general antioxidant, iron chelating, and sugar and fat absorption characteristics of green tea.
Methods: Patients with non-alcoholic fatty liver disease were randomly assigned to 2 groups for a double blind clinical trial. Patients in the intervention group received 550 milligrams of green tea tablets daily as well as nutritional education for 3 months. The control group received the same protocol with green tea replaced with placebo tablets.
Results: After 3 months, 45 participants (21 in the intervention and 24 in the placebo group) completed the follow-up. The change in body mass index (BMI), aspartate aminotransferase (AST), and fasting blood sugar (FBS) was significantly different between the 2 groups, while the change in total iron binding capacity (TIBC), ferritin, alanine transaminase (ALT), HOMA, and weight did not show a significant difference.
Conclusions: The difference between the 2 groups was mainly observed in anthropometrics, liver enzyme, and metabolic indicators, although the difference might not have been highlighted due to the effectiveness of routine treatments, that both groups received.

First Authors:
Seyed Mohammad Tabatabaee

Correspondence Authors:
Mohammad Reza Vafa

All Authors:
Seyed Mohammad Tabatabaee, Seyed Moayed Alavian, Leila Ghalichi, Seyed Mohammad Miryounesi, Kazem Mousavizadeh, Shima Jazayeri, , Mohammad Reza Vafa